TRANSFORM THE TREATMENT OF RHEUMATOID ARTHRITIS
A revolutionary new treatment for rheumatoid arthritis
The convergence of extraordinary advances in immunology, neuroscience, and engineering have resulted in the development of an entirely new treatment approach for rheumatoid arthritis: Neuroimmune Modulation. This device-based therapeutic approach includes a small, wireless, implantable device, the SetPoint System, that stimulates the vagus nerve—activating the body’s innate pathways to reduce inflammation and restore immunologic balance. 1-3
Restores Immune Setpoint
The SetPoint System is the only FDA-approved treatment for RA that is designed to activate the body’s natural pathways to reduce inflammation and balance the immune setpoint, providing a completely different way to manage RA. 1-3
Proven Safe and Effective
The SetPoint System is clinically proven to effectively treat RA for adults with moderately to severely active disease and inadequate response or intolerance to one or more biologics or targeted synthetic drugs. Device placement is safe and stimulation is well tolerated. 5
Reduces Treatment Burden
Once activated, the SetPoint Implant automatically delivers therapy for one minute each day for up to ten years, allowing those living with RA the freedom to enjoy life on their own terms.4 All you have to do is charge the Implant battery for a few minutes each week.
What is nerve stimulation?
Through extraordinary advances in immunology, neuroscience and bioengineering, SetPoint Medical has developed the first and only FDA-approved device to treat rheumatoid arthritis with nerve stimulation—called neuroimmune modulation.
Who safe & effective is it?
Through extraordinary advances in immunology, neuroscience and bioengineering, SetPoint Medical has developed the first and only FDA-approved device to treat rheumatoid arthritis with nerve stimulation—called neuroimmune modulation.
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SetPoint Medical Announces CMS Transitional Pass-Through Payment Approval for the SetPoint System, the Breakthrough Neuroimmune Modulation Platform
A surprising new treatment for rheumatoid arthritis | NPR
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2. van Maanen MA, et al. The cholinergic anti-inflammatory pathway: towards innovative treatment of rheumatoid arthritis. Nat Rev Rheumatol. 2009;5(4):229-232.
3. Kelly MJ, et al. Manipulation of the inflammatory reflex as a therapeutic strategy. Cell Rep Med. 2022;3(7):100696.
4. Peterson D, et al. Clinical safety and feasibility of a novel implantable neuroimmune modulation device for the treatment of rheumatoid arthritis: initial results from the randomized, double-blind, sham-controlled RESET-RA study. Bioelectron Med. 2024;10(1):8.
5. Data on file at SetPoint Medical