USING THE BODY’S OWN HEALING REFLEX

In 2002, SetPoint Medical’s co-founder, Dr. Kevin Tracey discovered a new biological pathway – the Inflammatory Reflex – that created the possibility of treating chronic autoimmune disease using electricity. The Inflammatory Reflex signals along the vagus nerve to maintain homeostasis in the immune system and maintain a healthy set point. This signaling modulates the release of cytokines that contribute to inflammation.

UNLOCKING THE RESTORATIVE POWER OF THE INFLAMMATORY REFLEX

The Inflammatory Reflex senses infection, tissue injury and inflammation and relays this information to the central nervous system, which then reflexively increases neural signaling peripherally through the vagus nerve. The signal is transmitted to a novel population of T cells in the spleen, which in turn direct effector cells including monocytes and macrophages to reduce their production of the mediators that initiate and perpetuate inflammation.

Since Dr. Tracey’s discovery, the Inflammatory Reflex has been characterized further in multiple peer-reviewed papers in prominent scientific journals, leading to development of potential therapies by activating the reflex to treat chronic diseases.