BIOENGINEERING BEYOND NEUROMODULATION

While most neuromodulation therapies provide an additional means of managing symptoms of chronic conditions, after bioengineering advances in bioelectronic medicine, a small implanted device now generates and delivers periodic digital doses to nerve bundles, creating a disease-fighting effect based on mechanisms similar to drug therapies.

MICROSTIMULATION DOSAGE AT PRECISELY THE RIGHT LOCATION

With the discovery of the Inflammatory Reflex, SetPoint Medical researchers set out to characterize the pathway and harness it for clinical use. They worked to define the fibers in the vagus nerve to directly impact the spleen with the most precise, effective bioelectronic dose.

Direct stimulation of the vagus nerve using an electrode in contact with the nerve provides the most effective and predictable stimulation of the Inflammatory Reflex versus near field stimulators outside the body.

Measured biomarkers indicated SetPoint Medical’s approach has achieved meaningful anti-inflammatory response though brief, intermittent low-level stimulation. The impact of this stimulation lasted more than 24 hours, similar to taking a pill once a day.