SetPoint Medical is a biomedical technology company headquartered in Valencia, CA pioneering new bioelectronic medicine therapies as a safe, cost-effective alternative to drugs and biologics for patients with debilitating autoimmune diseases.

The company’s therapy uses precise electrical pulses to stimulate the vagus nerve to activate the body’s innate “Inflammatory Reflex” for rheumatoid arthritis, Crohn’s disease and other chronic autoimmune diseases.

Digital doses – targeted pulses of electricity – activate the Inflammatory Reflex, the natural mechanism in the central nervous system that regulates the immune system, discovered by SetPoint co-founder Dr. Kevin Tracey.

Following proof-of-concept studies for treating rheumatoid arthritis using a modified off-the-shelf vagus nerve stimulator, SetPoint Medical’s first-of-its-kind, miniaturized pulse generator is currently undergoing clinical studies for rheumatoid arthritis under FDA’s Investigational Device Exemption. The company has also conducted an additional successful proof-of-concept study in Crohn’s disease as well as promising pre-clinical research in multiple sclerosis.

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